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At the end of 2018, about 1.2 million people in the United States were living with HIV. Some groups of people in the United States are more likely to get HIV than others because of many factors, including the status of their sex partners, their risk behaviors, and where they live.

When people get HIV and don't take HIV medicine, they will typically progress through three stages of disease, one after the other: 1) acute HIV infection; 2) clinical latency, and 3) acquired immunodeficiency syndrome (AIDS).

There are also different types of HIV. It is possible, though rare, for people who have one type of HIV to get another type of HIV also; this is called superinfection.

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General HIV Information

General HIV Information

HIV stands for human immunodeficiency virus. The virus can lead to acquired immunodeficiency syndrome, or AIDS, if not treated. Unlike some other viruses, the human body can’t get rid of HIV completely, even after treatment.

Right now, there is no cure for HIV. But with proper medical care, HIV can be effectively controlled. Treatment for HIV is called antiretroviral therapy or ART. If taken as prescribed, ART can dramatically prolong the lives of many people who have HIV and keep them healthy. Also, people with HIV who take HIV medicine as prescribed and keep an undetectable viral load will not transmit HIV through sex. Before the introduction of ART in the mid-1990s, people with HIV could progress to AIDS (the last stage of HIV infection) in a few years. Today, someone who gets an HIV diagnosis and starts treatment in the early stages of the disease can live nearly as long as someone who does not have HIV.

HIV attacks the body’s immune system , specifically the CD4 cells . These special cells help the immune system fight off infections. If HIV isn’t treated, it reduces the number of CD4 cells in the body. This damage to the immune system makes it harder and harder for the body to fight off infections and some other diseases.

If HIV infection isn’t treated, a person is more likely to get other infections or infection-related cancers. These opportunistic infections or cancers take advantage of a very weak immune system and make the person even sicker.

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Opportunistic illnesses are infections and infection-related cancers that are more common or more severe in people with HIV because their immune systems are damaged. Examples include Kaposi's sarcoma, lymphoma, tuberculosis, and pneumonia.

How HIV Is Transmitted

Only certain body fluids —from a person with HIV can transmit HIV. The body fluids that can transmit HIV are blood, semen (cum), pre-seminal fluid (pre-cum), rectal fluids, vaginal fluids, and breast milk. For transmission to occur, these fluids must come in contact with a mucous membrane or damaged tissue or be directly injected into the bloodstream (from a needle or syringe) of a person without HIV. Mucous membranes are found inside the rectum , vagina, penis, and mouth.

You can get or transmit HIV only through specific activities. Most commonly, people get or transmit HIV through sexual behaviors and needle or syringe use. However, there are ways to greatly reduce your risk of getting or transmitting HIV from these activities, such as

Learn more about how HIV is and isn’t transmitted in the United States.

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HIV is most often transmitted by